abstract：BACKGROUND:In 2007, the National Quality Forum (NQF) released four performance measures for the treatment of breast cancer. We proposed to study the degree of adherence with these measures among participating institutions in a multi-institutional trial. METHODS:American College of Surgeons Oncology Group (ACOSOG) Z001...

journal_title：Annals of surgical oncology

authors： Wilke LG,Ballman KV,McCall LM,Giuliano AE,Whitworth PW,Blumencranz PW,Reintgen DS,Burak WE,Leitch AM,Hunt KK

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Pancreatic cancer accounts for approximately 3% of cancer deaths in Europe. Locally advanced pancreatic cancer (LAPC) involves vascular structures, and resectability is low, with a median survival time of 6 to 11 months. We conducted a prospective, nonrandomized study of patients with LAPC to assess the effe...

journal_title：Annals of surgical oncology

authors： Polistina F,Costantin G,Casamassima F,Francescon P,Guglielmi R,Panizzoni G,Febbraro A,Ambrosino G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Intraoperative imprint cytology (IC) is one of several accurate, proven methods to detect tumor cells in sentinel lymph nodes (SLN) from patients with operable breast cancer. In patients treated with neoadjuvant chemotherapy (NAC), studies have demonstrated the feasibility and accuracy of SLN biopsy procedur...

journal_title：Annals of surgical oncology

authors： Gimbergues P,Dauplat MM,Durando X,Abrial C,Le Bouedec G,Mouret-Reynier MA,Cachin F,Kwiatkowski F,Tchirkov A,Dauplat J,Penault-Llorca F

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:CpG island methylator phenotype (CIMP), characterized by simultaneous methylation of multiple tumor suppressor genes (TSGs), has been reported to be associated with biological malignancy in many cancers. Whether CIMP is potentially predictive of clinical outcome in hepatocellular carcinoma (HCC) remains unkn...

journal_title：Annals of surgical oncology

authors： Li B,Liu W,Wang L,Li M,Wang J,Huang L,Huang P,Yuan Y

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The prognostic value of c-erbB-2 and vascular endothelial growth factor (VEGF) expression in colorectal liver metastases (CLM) is unclear. The purpose of this study was to clarify the relationship of c-erbB-2 and VEGF with the clinicopathological parameters and the survival results in CLM. METHODS:For 44 pa...

journal_title：Annals of surgical oncology

authors： Chen J,Li Q,Wang C,Wu J,Zhao G

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Recently, traditional laparoscopic anterior resection has been used for rectal cancer, offering good functional results compared with open resection and resulting in better early postoperative outcomes. Few studies investigating the role of robot-assisted tumor-specific rectal surgery (RTSRS) have been carri...

journal_title：Annals of surgical oncology

authors： Pigazzi A,Luca F,Patriti A,Valvo M,Ceccarelli G,Casciola L,Biffi R,Garcia-Aguilar J,Baek JH

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the frequency, pattern, and predictive factors associated with occult level II lymph node (LN) metastases in papillary thyroid carcinoma (PTC) patients with clinically metastatic lymph nodes in the lateral neck (level III, IV, and/or V) by preoperative ultrasonography...

journal_title：Annals of surgical oncology

authors： Koo BS,Seo ST,Lee GH,Kim JM,Choi EC,Lim YC

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Parenchyma-preserving resections (PPRs), including enucleation and middle pancreatectomy (MP), are accepted procedures for insulinomas, but their role in the treatment of nonfunctioning pancreatic endocrine tumors (NF-PETs) is debated. The aim of this study was to evaluate perioperative and long-term outcome...

journal_title：Annals of surgical oncology

authors： Falconi M,Zerbi A,Crippa S,Balzano G,Boninsegna L,Capitanio V,Bassi C,Di Carlo V,Pederzoli P

更新日期：2010-06-01 00:00:00

abstract：INTRODUCTION:Obesity adds to the technical difficulty of colorectal surgery and is a risk factor for postoperative complications. We hypothesized that obese patients have increased morbidity and poor oncologic outcomes after proctectomy for rectal adenocarcinoma. METHODS:Adult patients undergoing total mesorectal exci...

journal_title：Annals of surgical oncology

authors： Ballian N,Yamane B,Leverson G,Harms B,Heise CP,Foley EF,Kennedy GD

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The goal of this study was to determine the oncologic outcomes in localized resectable soft-tissue sarcoma after pre- versus postoperative radiation. METHODS:Literature searches through MEDLINE, EMBASE, CancerLit, and the Cochrane Database were performed with the following search terms: sarcoma, radiation, ...

journal_title：Annals of surgical oncology

authors： Al-Absi E,Farrokhyar F,Sharma R,Whelan K,Corbett T,Patel M,Ghert M

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDAC) frequently resists conventional cytotoxic therapy. The antitumor effects of endothelial monocyte-activating polypeptide II (EMAP) have been attributed to its antiendothelial and antiangiogenic activities. We tested the hypothesis that a combination of EMAP with bevaciz...

journal_title：Annals of surgical oncology

authors： Schwarz RE,Awasthi N,Konduri S,Cafasso D,Schwarz MA

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Notch1 regulates cell proliferation, development, and apoptosis. Aberrant expression of Notch1 has been discovered in many types of tumors. We examined Notch1 expression in colorectal cancer to assess its role as a prognostic indicator. METHODS:Notch1 protein expression was examined by immunohistochemistry ...

journal_title：Annals of surgical oncology

authors： Chu D,Li Y,Wang W,Zhao Q,Li J,Lu Y,Li M,Dong G,Zhang H,Xie H,Ji G

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) staging system for gastric cancer incorporates the absolute number of metastatic lymph nodes (N status) and is optimally used when >or=15 nodes are examined. The ratio of metastatic to examined nodes (N ratio) is an effec...

journal_title：Annals of surgical oncology

authors： Maduekwe UN,Lauwers GY,Fernandez-Del-Castillo C,Berger DL,Ferguson CM,Rattner DW,Yoon SS

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors of the pancreas, such as insulinoma, are difficult to localize, and complete resection is essential for cure. Our hypothesis is that a near-infrared (NIR) fluorophore exhibiting uptake in insulinoma could provide high-sensitivity detection intraoperatively. MATERIALS AND METHODS:The op...

journal_title：Annals of surgical oncology

authors： Winer JH,Choi HS,Gibbs-Strauss SL,Ashitate Y,Colson YL,Frangioni JV

更新日期：2010-04-01 00:00:00

abstract：INTRODUCTION:Lymphatic drainage patterns from the breast have been described in the past. Drainage may change after treatment of a breast or axilla, and this may have implications for lymphatic mapping. The aim of this study was to determine the lymphatic drainage patterns in breast cancer patients with a previously tr...

journal_title：Annals of surgical oncology

authors： van der Ploeg IM,Oldenburg HS,Rutgers EJ,Baas-Vrancken Peeters MJ,Kroon BB,Valdés Olmos RA,Nieweg OE

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study is to establish the validity of F-18-deoxyglucose positron emission tomography-computed tomography (FDG-PET-CT) scan staging for cutaneous melanoma when a musculoskeletal image abnormality is detected. METHODS:An institutional review board (IRB)-approved prospective database was qu...

journal_title：Annals of surgical oncology

authors： Mansour AA 3rd,Kelley MC,Hatmaker AR,Holt GE,Schwartz HS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The goal of this multicenter study was to clarify the determinants of local excision for patients with T1-T2 lower rectal cancer. METHODS:Data from 567 consecutive patients who underwent radical resection for T1-T2 lower rectal cancer at 12 institutions between 1991 and 1998 were reviewed. Rates of lymph no...

journal_title：Annals of surgical oncology

authors： Kobayashi H,Mochizuki H,Kato T,Mori T,Kameoka S,Shirouzu K,Saito Y,Watanabe M,Morita T,Hida J,Ueno M,Ono M,Yasuno M,Sugihara K

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Although hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, the underlying molecular mechanisms contributing to hepatocarcinogenesis are still not clear. METHODS:In this study, we performed double array analysis, consisting of both expression profiling and karyotyping analysis using s...

journal_title：Annals of surgical oncology

authors： Nomoto S,Kanda M,Okamura Y,Nishikawa Y,Qiyong L,Fujii T,Sugimoto H,Takeda S,Nakao A

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Isolated hepatic perfusion (IHP) of chemotherapy has been proposed to deliver high doses of drug while avoiding systemic toxicity. Hypotonic cisplatin has a high in vitro activity on human colon cancer cells. We studied the safety of a 30-min hypoxic single-pass IHP with hypotonic cisplatin. METHODS:A preli...

journal_title：Annals of surgical oncology

authors： Ortega-Deballon P,Facy O,Consolo D,Magnin G,Tixier H,Simonet M,Rat P,Chauffert B

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:Inguinal lymphadenectomy for metastatic melanoma is reported to have a complication rate as high as 50%. Wound dehiscence has been reported to occur in more than half of these patients, and as a result many surgeons routinely use sartorius muscle transposition to protect against the potential for exposed v...

journal_title：Annals of surgical oncology

authors： Delman KA,Kooby DA,Ogan K,Hsiao W,Master V

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Preoperative chemoradiotherapy has been widely adopted as the standard of care for stage II-III rectal cancers. However, patients with T3N0 lesions had been shown to have a better prognosis than other categories of locally advanced tumor. Thus, neoadjuvant chemoradiation is likely to be overtreatment in this...

journal_title：Annals of surgical oncology

authors： Lombardi R,Cuicchi D,Pinto C,Di Fabio F,Iacopino B,Neri S,Tardio ML,Ceccarelli C,Lecce F,Ugolini G,Pini S,Di Tullio P,Taffurelli M,Minni F,Martoni A,Cola B

更新日期：2010-03-01 00:00:00

abstract：AIMS:To determine the incidence of lymph node (LN) metastasis in patients with apparently early carcinosarcoma of the uterus, to analyze the clinicopathologic factors associated with LN metastasis, and to evaluate the role of pelvic and/or para-aortic lymphadenectomy in treatment of such conditions. METHODS:We retrosp...

journal_title：Annals of surgical oncology

authors： Park JY,Kim DY,Kim JH,Kim YM,Kim YT,Nam JH

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS:Genomic mutation and pr...

journal_title：Annals of surgical oncology

authors： Yamasaki M,Miyata H,Fujiwara Y,Takiguchi S,Nakajima K,Nishida T,Yasuda T,Matsuyama J,Mori M,Doki Y

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:In case of liver tumors invading the middle hepatic vein (MHV) at the hepatocaval confluence (HC) major resection is recommended. We describe a new ultrasound-guided conservative operation for patients with colorectal liver metastasis (CLM) invading the MHV at the HC. METHODS:The case of a 65-year-old woman...

journal_title：Annals of surgical oncology

authors： Torzilli G,Botea F,Donadon M,Cimino M,Del Fabbro D,Palmisano A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Malignant ascites (MA) is a distressing problem usually managed by repeated paracenteses. Paracentesis represents a meaningful time point in identifying patients with a specific presentation. OBJECTIVE:The objective of this study is to examine symptom clustering in MA patients at paracentesis. METHODS:Pre-...

journal_title：Annals of surgical oncology

authors： Husain A,Bezjak A,Easson A

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Consensus guidelines recommend prolonged thromboprophylaxis for up to 4 weeks after major abdominopelvic cancer operations. Several factors impede widespread adoption of these guidelines. These include lack of awareness, cost, increased bleeding complications, increased incidence of heparin-induced thrombocy...

journal_title：Annals of surgical oncology

authors： Bradley CT,Brasel KJ,Miller JJ,Pappas SG

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The rarity of melanoma in young patients, particularly pediatric ones, has to date precluded any valid comparisons being made between young patients and adults undergoing sentinel lymph node biopsy (SLNB) for intermediate thickness localized melanoma. The present study takes advantage of the large Sydney Mel...

journal_title：Annals of surgical oncology

authors： Howman-Giles R,Shaw HM,Scolyer RA,Murali R,Wilmott J,McCarthy SW,Uren RF,Thompson JF

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Low-dose rate brachytherapy is a well-established adjuvant treatment for soft tissue sarcomas (STS). The experience with high-dose rate brachytherapy (HDR BT) in this indication is limited. The purpose of our study was to evaluate the viability of perioperative hyperfractionated HDR BT for STS. METHODS:Fort...

journal_title：Annals of surgical oncology

authors： Petera J,Soumarová R,Růzicková J,Neumanová R,Dusek L,Sirák I,Macingová Z,Paluska P,Kasaová L,Hodek M,Vosmik M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Improved survival has been reported for diffuse malignant peritoneal mesothelioma (DMPM) treated by surgical cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC). The significance of lymph node involvement in this disease is still poorly understood. METHODS:Prospectively collected clinical da...

journal_title：Annals of surgical oncology

authors： Baratti D,Kusamura S,Cabras AD,Laterza B,Balestra MR,Deraco M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). Although the absolute number of nodes involved with cancer is important for prognosis, the role of the total number of excised nodes ...

journal_title：Annals of surgical oncology

authors： Hatoum HA,Jamali FR,El-Saghir NS,Musallam KM,Seoud M,Dimassi H,Abbas J,Khalife M,Boulos FI,Tawil AN,Geara FB,Salem Z,Shamseddine AA,Al-Feghali K,Shamseddine AI

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:This study compared two homogeneous groups of patients submitted to either surgical resection (HR) or laparoscopic radiofrequency ablation (LRFA) for the treatment of hepatocellular carcinoma (HCC). When compatible with the liver functional reserve, HR remains the treatment of choice for HCC, while LRFA seem...

journal_title：Annals of surgical oncology

authors： Santambrogio R,Opocher E,Zuin M,Selmi C,Bertolini E,Costa M,Conti M,Montorsi M

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The prognosis of gastric cancer patients with peritoneal dissemination is poor. Recently, chemotherapy with S-1 plus cisplatin has been shown to be highly effective for advanced gastric cancer. METHODS:In 41 patients diagnosed with either macro- or microscopic peritoneal dissemination by staging laparoscopy...

journal_title：Annals of surgical oncology

authors： Okabe H,Ueda S,Obama K,Hosogi H,Sakai Y

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Pancreatic metastases are uncommon and little is known about the oncologic outcome after resection or prognostic parameters. This study was designed to evaluate perioperative and follow-up results after resection for pancreatic metastases and to define prognostic factors. METHODS:From a prospective database...

journal_title：Annals of surgical oncology

authors： Strobel O,Hackert T,Hartwig W,Bergmann F,Hinz U,Wente MN,Fritz S,Schneider L,Büchler MW,Werner J

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) biopsy has been suggested as an independent prognostic factor in patients with breast cancer. METHODS:Patients operated for breast cancer from June 2000 to April 2008 were enrolled in this protocol after signing an informed consent. After primary surgery, BM aspirate from the iliac crest wa...

journal_title：Annals of surgical oncology

authors： Fortunato L,Mascaro A,Baldi A,Farina M,Cortese G,Ventrone MA,Amini M,Vitelli C

更新日期：2009-11-01 00:00:00

abstract：AIM:We evaluated preoperative serum carcinoembryonic antigen (CEA) as a prognostic factor for colorectal cancer and determined when surveillance of this marker was useful. METHODS:Serum CEA was measured preoperatively in 1,263 patients who underwent curative resection for colorectal cancer at 3-month intervals for the...

journal_title：Annals of surgical oncology

authors： Park IJ,Choi GS,Lim KH,Kang BM,Jun SH

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Perioperative nutrition remains a significant problem in patients undergoing neoadjuvant treatment for esophageal cancer. The aim of this study was to evaluate the effectiveness of esophageal stenting, feeding tube placement, or observation among esophageal cancer patients receiving neoadjuvant therapy. MET...

journal_title：Annals of surgical oncology

authors： Bower M,Jones W,Vessels B,Scoggins C,Martin R

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Recent adjuvant chemotherapy trials after resection of stage II and III non-small cell lung cancer (NSCLC) have identified important survival differences among patients with immunohistochemical evidence suggesting platinum resistance. No clinical information exists regarding the impact upon survival of patie...

journal_title：Annals of surgical oncology

authors： d'Amato TA,Pettiford BL,Schuchert MJ,Parker R,Ricketts WA,Luketich JD,Landreneau RJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Field cancerization is a feature of HNSCCs. No biological marker in the index tumor has correlated with second primary tumor (SPTs) development. Changes in MDM-2 and epidermal growth factor receptor (EGFR) expression are known to be early neoplastic changes in HNSCC. EGFR expression is correlated with clinic...

journal_title：Annals of surgical oncology

authors： Farhadieh RD,Salardini A,Rees CG,Russell PJ,Yang JL,Smee R

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDAC) are well known. Genetic and epigenetic data were correlated with tumor biology to find specific alterations responsible for invasion and metastasis in pancreatic ductal adenocarcinomas. METHODS:A total of 16 hu...

journal_title：Annals of surgical oncology

authors： Mees ST,Mardin WA,Sielker S,Willscher E,Senninger N,Schleicher C,Colombo-Benkmann M,Haier J

更新日期：2009-08-01 00:00:00

abstract：INTRODUCTION:Sentinel lymph node mapping (SLNM) with multilevel sections (MLS) and cytokeratin immunohistochemistry (CK-IHC) of sentinel lymph nodes (SLNs) upstages 15-20% of patients (pts). False-positive SLNs occur in breast cancer due to mechanical transport of cells during mapping procedures, or to pre-existing ben...

journal_title：Annals of surgical oncology

authors： Wiese D,Saha S,Yestrepsky B,Korant A,Sirop S

更新日期：2009-08-01 00:00:00